LU-005i

Names

[ CAS No. ]:
1620107-33-6

[ Name ]:
LU-005i

Biological Activity

[Description]:

LU-005i is a potent inhibitor of β5i subunit of immunoproteasomes (IC50 = 6.6 nM), selective over β5c subunit (IC50 = 287 nM)[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[Target]

β5i subunit of immunoproteasomes (IC50 = 6.6 nM), β5c subunit of immunoproteasomes (IC50 = 287 nM)[1]

[References]

[1]. Rezvan Moallemian, et al. Immunoproteasome inhibitor DPLG3 attenuates experimental colitis by restraining NF-κB activation.Biochem Pharmacol. 2020 Jul:177:113964.

Chemical & Physical Properties

[ Density]:
1.189±0.06 g/cm3(Predicted)

[ Boiling Point ]:
860.2±65.0 °C(Predicted)

[ Molecular Formula ]:
C₃₁H₄₆N₄O₇

[ Molecular Weight ]:
586.72

Related Compounds

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