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HJC0416

Names

[ CAS No. ]:
1617518-22-5

[ Name ]:
HJC0416

Biological Activity

[Description]:

A orally bioavailable small-molecule STAT3 inhibitor; inhibits the proliferation of both ER-positive, and ER-negative (triple negative) breast cancer cells with IC50 values of 1.76 uM and 1.97 uM, respectively; inhibits cell cycle progression and promotes apoptosis both in vitro and in vivo.

[References]

References 1. Chen H, et al. Eur J Med Chem. 2014 Jul 23;82:195-203. View Related Products by Target STAT

Chemical & Physical Properties

[ Molecular Formula ]:
C18H17ClN2O4S

[ Molecular Weight ]:
392.854


Related Compounds

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