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SCHEMBL18811643

Names

[ CAS No. ]:
161485-82-1

[ Name ]:
SCHEMBL18811643

Biological Activity

[Description]:

MMAF intermediate 1 is an intermediate in the synthesis of MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent inhibitor of tubulin polymerization and the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs), such as Vorsetuzumab mafodotin and SGN-CD19A[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1].  

Chemical & Physical Properties

[ Molecular Formula ]:
C24H36N2O6

[ Molecular Weight ]:
448.55


Related Compounds

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