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Avacincaptad pegol

Names

[ CAS No. ]:
1613641-69-2

[ Name ]:
Avacincaptad pegol

Biological Activity

[Description]:

Avacincaptad pegol is a C5 complement inhibitor that may reduce inflammation-related retinal pigment epithelium (RPE) damage. Avacincaptad pegol caqn be used for the research of stargardt macular dystrophy (STGD1) and geographic atrophy (GA)[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Immunology/Inflammation >> Complement System
Research Areas >> Inflammation/Immunology

[References]

[1]. Rehan M Hussain, et al. Stargardt macular dystrophy and evolving therapies. Expert Opin Biol Ther. 2018 Oct;18(10):1049-1059.  

[2]. Glenn J Jaffe, et al. C5 Inhibitor Avacincaptad Pegol for Geographic Atrophy Due to Age-Related Macular Degeneration: A Randomized Pivotal Phase 2/3 Trial. Ophthalmology. 2021 Apr;128(4):576-586.  

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds