KBP-7018

Names

[ Name ]:
KBP-7018

Biological Activity

[Description]:

A novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively; also potently inhibits FLT3, VEGFR2, Fyn, PDGFRα and VEGFR2; shows promising outcomes for the treatments of idiopathic pulmonary fibrosis (IPF).

[References]

References 1. Huang Z, et al. ACS Med Chem Lett. 2017 Sep 30;8(11):1142-1147. 2. Huang Z, et al. Drug Des Devel Ther. 2015 Aug 5;9:4319-28. View Related Products by Target c-Kit

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₃₀N₄O₅

[ Molecular Weight ]:
538.604

Related Compounds

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