QC-3611

Names

[ Name ]:
QC-3611

[Synonym ]:
2-{5-[(4-Chloro-2-Methylphenyl)methoxy]-1h-Pyrazol-1-Yl}pyridine-4-Carboxylic Acid
2-{5-[(4-Chloro-2-methylbenzyl)oxy]-1H-pyrazol-1-yl}isonicotinic acid
4-Pyridinecarboxylic acid, 2-[5-[(4-chloro-2-methylphenyl)methoxy]-1H-pyrazol-1-yl]-

Biological Activity

[Description]:

QC-3611 is a selective inhibitor of JARID1A/1B, which is a target existing in various tumors (JARID1A IC50 = 13 nM ;JARID1B IC50 = 2 nM). QC-3611 is promisingly to be used as an antineoplastic drug.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
620.3±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₄ClN₃O₃

[ Molecular Weight ]:
343.764

[ Flash Point ]:
328.9±31.5 °C

[ Exact Mass ]:
343.072357

[ LogP ]:
4.36

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.645

Related Compounds

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