(1S,2S)-2-PCCA

Names

[ Name ]:
(1S,2S)-2-PCCA

[Synonym ]:
(1S,2S)-N-[(2S,3S)-2-Amino-3-methylpentyl]-N-(4'-propyl-4-biphenylyl)-2-(2-pyridinyl)cyclopropanecarboxamide
Cyclopropanecarboxamide, N-[(2S,3S)-2-amino-3-methylpentyl]-N-(4'-propyl[1,1'-biphenyl]-4-yl)-2-(2-pyridinyl)-, (1S,2S)-

Biological Activity

[Description]:

The (1R,2R) diastereomer of 2-PCCA, a potent, selective agonist of the orphan GPR88 receptor with EC50 of 373 nM, 5-fold more potent than the (1S, 2S)-isomer.

[References]

References 1. Jin C, et al. ACS Chem Neurosci. 2014 Jul 16;5(7):576-87. View Related Products by Target GPR88

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
623.4±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₀H₃₇N₃O

[ Molecular Weight ]:
455.634

[ Flash Point ]:
330.8±31.5 °C

[ Exact Mass ]:
455.293671

[ LogP ]:
5.61

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.601

Related Compounds

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