Dap-NE

Names

[ CAS No. ]:
160800-82-8

[ Name ]:
Dap-NE

[Synonym ]:
2-Pyrrolidinepropanamide, N-[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]-β-methoxy-α-methyl-, (αR,βR,2S)-
(2R,3R)-N-[(1S,2R)-1-Hydroxy-1-phenyl-2-propanyl]-3-methoxy-2-methyl-3-[(2S)-2-pyrrolidinyl]propanamide

Biological Activity

[Description]:

Dap-NE is an intermediate reagent in the synthesis of the ADC toxin Monomethyl auristatin E (HY-15162)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Xiao Chao, et al. Monomethyl auristatin E single crystal as standard or reference substance and preparation method thereof. China, CN116768966 A. 2023-09-19.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
527.8±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H28N2O3

[ Molecular Weight ]:
320.427

[ Flash Point ]:
273.0±30.1 °C

[ Exact Mass ]:
320.209991

[ LogP ]:
1.06

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.531

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.