Elcatonin acetate

Names

[ Name ]:
Elcatonin acetate

Biological Activity

[Description]:

Elcatonin (Carbocalcitonin) acetate is a synthetic analog of eel calcitonin. Elcatonin acetate increases bone mineral density, inhibits bone resorption and processes a central analgesic effect[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[In Vivo]

Elcatonin (Carbocalcitonin) acetate (20 U/kg; s.c.; 2 d after oxaliplatin administration)attenuats oxaliplatin-induced cold and mechanical allodynia in rats[1]. Animal Model: Male Sprague-Dawley rats weighing 150-250 g (Oxaliplatin-Induced Allodynia Models)[1] Dosage: 20 U/kg Administration: Subcutaneously; 2 d after oxaliplatin administration Result: Attenuated oxaliplatin-induced cold in rtas.

[References]

[1]. Knopp JA, et al. Calcitonin for treating acute pain of osteoporotic vertebral compression fractures: a systematic review of randomized, controlled trials. Osteoporos Int. 2005;16(10):1281‐1290.

[2]. Aoki M,et al. Comparison of the effects of single doses of elcatonin and pregabalin on oxaliplatin-induced cold and mechanical allodynia in rats. Biol Pharm Bull. 2014;37(2):322‐326.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅₀H₂₄₈N₄₂O₄₉

[ Molecular Weight ]:
3423.83

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.