Nelipepimut-S

Names

[ CAS No. ]:
160212-35-1

[ Name ]:
Nelipepimut-S

[Synonym ]:
NeuVax
L-Lysyl-L-isoleucyl-L-phenylalanylglycyl-L-seryl-L-leucyl-L-alanyl-L-phenylalanyl-L-leucine
Nelipepimut-S
E75 peptide
7M0A29CD8B
human receptor tyrosine-protein kinase erbB-2 (proto-oncogene Neu, tyrosine kinase- type cell surface receptor HER2, CD340)-(347-355)-peptide
L-Leucine, L-lysyl-L-isoleucyl-L-phenylalanylglycyl-L-seryl-L-leucyl-L-alanyl-L-phenylalanyl-

Biological Activity

[Description]:

Nelipepimut-S is a peptide vaccine which targets HER2. Nelipepimut-S has immune activity against HER2 positive breast cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> JAK/STAT Signaling >> EGFR
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR

[Target]

HER2


[References]

[1]. Dillon PM, et al. Evaluating Nelipepimut-S in the Treatment of Breast Cancer: A Short Report on the Emerging Data. Breast Cancer (Dove Med Press). 2020 Apr 3;12:69-75.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
1354.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C50H78N10O11

[ Molecular Weight ]:
995.215

[ Flash Point ]:
773.0±34.3 °C

[ Exact Mass ]:
994.585144

[ LogP ]:
4.02

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.555

Related Compounds

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