Ulipristal

Names

[ Name ]:
Ulipristal

[Synonym ]:
6J5J15Q2X8
Deacetyl CDB 2914
Ulipristal [USAN:INN:BAN]
(11β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-19-norpregna-4,9-diene-3,20-dione
Ulipristal (USAN/INN)
Ulipristal,11beta-[4-(N,N-diMethylaMino)-phenyl]-17alpha-hydroxy-19-norpregna-4,9-diene-3,20-dione
Estra-4,9-dien-3-one, 17-acetyl-11-[4-(dimethylamino)phenyl]-17-hydroxy-, (11β,17α)-
Ulipristal

Biological Activity

[Description]:

Ulipristal (CDB 3236) is a selective progesterone receptor modulator (SPRM). Ulipristal binds to the progesteron receptor, thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system[1].

[Related Catalog]:

Signaling Pathways >> Others >> Progesterone Receptor

Research Areas >> Cancer

Research Areas >> Endocrinology

[In Vivo]

Ulipristal (CDB 3236) may suppress the growth of uterine leiomyomatosis. By inhibiting or delaying ovulation and effecting endometrial tissue, ulipristal can be used as an emergency contraception[1].

[References]

[1]. LIANA PLES, et al. Is Ulipristal Acetate a Liver Toxic Biomolecule? Toxicity assessment of ulipristal acetate. REV.CHIM.(Bucharest).

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
638.5±55.0 °C at 760 mmHg

[ Melting Point ]:
183.5-184.5ºC /Losartan/

[ Molecular Formula ]:
C₂₈H₃₅NO₃

[ Molecular Weight ]:
433.582

[ Flash Point ]:
340.0±31.5 °C

[ Exact Mass ]:
433.261688

[ PSA ]:
57.61000

[ LogP ]:
3.86

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.613

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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