Furosine dihydrochloride

Names

[ Name ]:
Furosine dihydrochloride

[Synonym ]:
L-Lysine, N6-[2-(2-furanyl)-2-oxoethyl]-, hydrochloride (1:2)
N6-[2-(2-Furyl)-2-oxoethyl]-L-lysine dihydrochloride

Biological Activity

[Description]:

Furosine dihydrochloride, an amino acid derivative, is an important chemical marker of early-stage Maillard reactions. Furosine dihydrochloride is closely related to a variety of diseases such as diabetes[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[In Vitro]

Furosine could degrade slowly to form many different advanced glycation end products (AGEs). Partial AGEs have been proven to be closely related to a variety of diseases, such as diabetes, and a high amount of AGEs in human bodies is considered harmful[1].

[References]

[1]. Li Y, et, al. Qualitative and quantitative analysis of furosine in fresh and processed ginsengs. J Ginseng Res. 2018 Jan;42(1):21-26.

[2]. Poojary MM, et, al. Liquid chromatography quadrupole-Orbitrap mass spectrometry for the simultaneous analysis of advanced glycation end products and protein-derived cross-links in food and biological matrices. J Chromatogr A. 2020 Mar 29;1615:460767.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₂₀Cl₂N₂O₄

[ Molecular Weight ]:
327.204

[ Exact Mass ]:
326.080017

Related Compounds

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