pTH (1-31) (human)

Names

[ Name ]:
pTH (1-31) (human)

[Synonym ]:
PTH (1-31) (HUMAN)

Biological Activity

[Description]:

Human PTH-(1-31) is the 1-31 fragment of human PTH. Human PTH-(1-31) stimulates the release of cAMP and also is a weaker stimulator of the 25-hydroxyvitamin D-1α-hydroxylase. Human PTH-(1-31) induces bone formation without inducing bone resorption. Human PTH-(1-31) has the potential for the research of osteoporosis[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Thyroid Hormone Receptor

Research Areas >> Metabolic Disease

[References]

[1]. Fraher LJ, et al. Comparison of the biochemical responses to human parathyroid hormone-(1-31)NH2 and hPTH-(1-34) in healthy humans. J Clin Endocrinol Metab. 1999 Aug;84(8):2739-43.

[2]. K. Henriksen, et al. Evaluation of the efficacy, safety and pharmacokinetic profile of oral recombinant human parathyroid hormone [rhPTH(1-31)NH2] in postmenopausal women with osteoporosis. Bone. 2013, 53 (1): 160-166.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆₂H₂₆₉N₄₉O₄₇S₂

[ Storage condition ]:
-15°C

pTH (1-31) (human)

Names

Biological Activity

Chemical & Physical Properties

Related Compounds