Procaspase-6 inhibitor 13

Names

[ Name ]:
Procaspase-6 inhibitor 13

Biological Activity

[Description]:

Procaspase-6 inhibitor 13 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.38 uM.Procaspase-6 inhibitor 13 binds to pro-C6 at the dimer interface and contacts amino acids Y198, T199 and E214.Procaspase-6 inhibitor 13 significantly stabilizes procaspase-6.

[References]

1. Jeremy Murray, et al. ChemMedChem. 2014 Jan;9(1):73-7, 2.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₄FN₅O

[ Molecular Weight ]:
311.32

Related Compounds

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