Sel-green

Names

[ Name ]:
Sel-green

Biological Activity

[Description]:

Sel-green, a selective selenol fluorescent probe, is applied to quantify the Sec content in the selenoenzyme thioredoxin reductase and image endogenous Sec in live HepG2 cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

Sel-green displays >20-fold selectivity of Sec over DTT[1]. Sel-green is suitable for identifying the selenol species metabolized from various selenocompounds in cells, which helps to clarify the mechanism underlying the cytotoxicity of different selenocompounds[1].

[References]

[1]. Baoxin Zhang, et al. Selective selenol fluorescent probes: design, synthesis, structural determinants, and biological applications. J Am Chem Soc. 2015 Jan 21;137(2):757-69.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₈N₄O₈S

[ Molecular Weight ]:
462.43

Related Compounds

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