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Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2

Names

[ CAS No. ]:
157382-69-9

[ Name ]:
Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2

[Synonym ]:
N-Acetyl-L-α-aspartyl-O-phosphono-L-tyrosyl-L-valyl-L-prolyl-L-methionyl-L-leucinamide
L-Leucinamide, N-acetyl-L-α-aspartyl-O-phosphono-L-tyrosyl-L-valyl-L-prolyl-L-methionyl-

Biological Activity

[Description]:

Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2 is the SH2 domain ligand. SH2 domains participate in protein tyrosine kinase (PTK)-mediated cellular signal[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Burke TR Jr, et al. Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain inhibitors. Biochemistry. 1994 May 31;33(21):6490-4.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C36H56N7O13PS

[ Molecular Weight ]:
857.908

[ Exact Mass ]:
857.339417

[ LogP ]:
0.55

[ Index of Refraction ]:
1.572

Related Compounds