trimethyl-[3-[4-[(3-methyl-1,3-benzothiazol-2-ylidene)methyl]quinolin-1-ium-1-yl]propyl]azanium,diiodide

Names

[ CAS No. ]:
157199-59-2

[ Name ]:
trimethyl-[3-[4-[(3-methyl-1,3-benzothiazol-2-ylidene)methyl]quinolin-1-ium-1-yl]propyl]azanium,diiodide

[Synonym ]:
Quinolinium,4-[(3-methyl-2(3H)-benzothiazolylidene)methyl]-1-[3-(trimethylammonio)propyl]-,diiodide (9CI)
TO-PRO 1
3-METHYL-2-([1-[3-(TRIMETHYLAMMONIO)PROPYL]-4-1H-QUINOLINYLIDENE]METHYL)-1,3-BENZOTHIAZOL-3-IUM DIIODIDE
Quinolinium,4-[(3-methyl-2(3H)-benzothiazolylidene)methyl]-1-[3-(trimethylammonio)propyl]-,iodide (1:2)

Biological Activity

[Description]:

TO-PRO 1 is a DNA binding fluorochrome, that atached to the surface of the Feraheme (FH) nanoparticle (NP), to obtain a fluorochrome-functionalized NP. TO-PRO 1 binds DNA through intercalation, and acts as a vital fluorochrome for necrotic cells[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Hoonsung Cho, et al. Fluorochrome-functionalized nanoparticles for imaging DNA in biological systems. ACS Nano. 2013 Mar 26;7(3):2032-41.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H29I2N3S

[ Molecular Weight ]:
645.38100

[ Exact Mass ]:
645.01700

[ PSA ]:
37.05000

Related Compounds

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