Vabametkib

Names

[ CAS No. ]:
1571903-56-4

[ Name ]:
Vabametkib

Biological Activity

[Description]:

Vabametkib is a potent inhibitor of hepatocyte growth factor receptor (HGFR). Vabametkib inhibits Hs746T cells proliferation and inhibits c-Met with an IC50 value of 7 nM. Vabametkib can be used as an antineoplastic agent[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Met/HGFR

[References]

[1]. WHO Drug Informat ion - World Health Organization (WHO).

[2]. Jung Hui Jeong, et al. Preparation of triazolopyrazine derivatives as c-Met kinase inhibitors: Korea, Republic of, KR2014022229. 2014-02-24.

[3]. WHO Drug Information-World Health Organization (WHO).

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₃₄N₁₂O

[ Molecular Weight ]:
566.66

Related Compounds

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