U-89843A

Names

[ Name ]:
U-89843A

[Synonym ]:
PNU 89843
7H-Pyrrolo[2,3-d]pyrimidine, 6,7-dimethyl-2,4-di-1-pyrrolidinyl-, hydrochloride (1:1)
6,7-Dimethyl-2,4-di(pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine hydrochloride (1:1)
6,7-Dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine hydrochloride
6,7-Dimethyl-2,4-di(1-pyrrolidinyl)-7H-pyrrolo[2,3-d]pyrimidine hydrochloride (1:1)

Biological Activity

[Description]:

U-89843A is an allosteric modulator of GABAA receptor. U-89843A enhances GABA-induced Cl- currents[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> GABA Receptor

[Target]

GABAA receptor[1]

[References]

[1]. Im HK, Im WB, et al. U-89843A is a novel allosteric modulator of gamma-aminobutyric acidA receptors. J Pharmacol Exp Ther. 1995 Dec;275(3):1390-5.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₂₄ClN₅

[ Molecular Weight ]:
321.85

[ Exact Mass ]:
321.172028

Related Compounds

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