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FV-162

Names

[ CAS No. ]:
1565822-28-7

[ Name ]:
FV-162

Biological Activity

[Description]:

A potent, orally bioavailable, irreversible proteasome inhibitor with potent antimyeloma activity (IC50<60 nM); induces rapid, irreversible inhibition of chymotrypsin-like proteasome activity in murine red blood cells and inhibits tumor growth in myeloma xenograft model.

[References]

References 1. Wang Z, et al. Cell Death Dis. 2015 Jul 9;6:e1815. View Related Products by Target Proteasome

Chemical & Physical Properties

[ Molecular Formula ]:
C25H28F4N4O7S

[ Molecular Weight ]:
604.574


Related Compounds

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