RORγt inhibitor 1

Names

[ CAS No. ]:
1561770-72-6

[ Name ]:
RORγt inhibitor 1

Biological Activity

[Description]:

RORγt inhibitor 1 is a RORγt allosteric inhibitor with an IC50 value of 1 nM.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> ROR

Research Areas >> Inflammation/Immunology

[References]

[1]. Zhang H, et al. Discovery of N-(Indazol-3-yl)piperidine-4-carboxylic Acids as RORγt Allosteric Inhibitors for Autoimmune Diseases. ACS Med Chem Lett. 2020 Jan 9;11(2):114-119.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₁ClFN₃O₄

[ Molecular Weight ]:
457.88

Related Compounds

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