4-HYDROXYPHENYLGLYOXYLICACID

Names

[ Name ]:
4-HYDROXYPHENYLGLYOXYLICACID

[Synonym ]:
(4-hydroxyphenyl)(oxo)acetic acid
p-hydroxybenzoylformic acid
2-(4-hydroxyphenyl)-2-oxoacetic acid
Pisolithin A
p-hydroxyphenylpyruvic acid
2-(4-hydroxyphenyl)glyoxylic acid
4-Hydroxyphenylglyoxylate
4-hydroxybenzoylformate
4-Hydroxyphenylglyoxylicacid

Biological Activity

[Description]:

4-Hydroxyphenylglyoxylate (4-Hydroxyphenylglyoxylic acid) is an inhibitor of carnitine palmitoyltransferase I (CPT I). 4-Hydroxyphenylglyoxylate can be used to study sensitivity changes in CPT I of liver mitochondria and fatty acid oxidation by isolated hepatocytes. 4-Hydroxyphenylglyoxylate can inhibits fatty acid oxidation[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Stephens TW, et al. Effect of starvation and diabetes on the sensitivity of carnitine palmitoyltransferase I to inhibition by 4-hydroxyphenylglyoxylate. Biochem J. 1987 Apr 15;243(2):405-12.

Chemical & Physical Properties

[ Density]:
1.457g/cm3

[ Boiling Point ]:
358.9ºC at 760mmHg

[ Molecular Formula ]:
C₈H₆O₄

[ Molecular Weight ]:
166.13100

[ Flash Point ]:
185ºC

[ Exact Mass ]:
166.02700

[ PSA ]:
74.60000

[ LogP ]:
0.65950

[ Vapour Pressure ]:
8.95E-06mmHg at 25°C

Safety Information

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%