Amyloid β-Protein (16-20) trifluoroacetate salt

Names

[ Name ]:
Amyloid β-Protein (16-20) trifluoroacetate salt

[Synonym ]:
lys-leu-val-phe-phe
klvff

Biological Activity

[Description]:

β-Amyloid peptide(16-20) is a amino acid sequences (KLVFF) of Amyloid-β (Abeta). β-Amyloid peptide(16-20) is an effective inhibitor of Abeta fibril formation, with RG-/-GR-NH2 residues added at N- and C-terminal ends to aid solubility)[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[In Vitro]

β-Amyloid peptide(16-20) (-NH2) 在 1:2 摩尔比 (Aβ40/peptide) 的剂量下，共孵育 12 天后 (37 ℃)，抑制 Abeta 原纤维形成)[1]。

[References]

[1]. Austen BM, et al. Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's beta-amyloid peptide. Biochemistry. 2008 Feb 19;47(7):1984-92.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₅H₅₂N₆O₆

[ Molecular Weight ]:
652.82

[ Exact Mass ]:
652.39500

[ PSA ]:
205.74000

[ LogP ]:
4.61820

Related Compounds

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