Regavirumab

Names

[ Name ]:
Regavirumab

Biological Activity

[Description]:

Regavirumab (MCA C23) is a human monoclonal antibody against cytomegalovirus (CMV), human serum albumin (HSA) and amino acetic acid[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> CMV

[In Vivo]

注射 Regavirumab 后获得的大鼠血清显示出强大的抑制斑块形成的活性[1]。 Regavirumab (2 mg/kg/周，5次)，第4次注射后24 h, Regavirumab 血药浓度达到稳定状态 (74.4±11.8 μg/mL)。末次注射后的消除半衰期与单次注射后相似[1]。

[References]

[1]. Arizono H, et al. Pharmacokinetics of a new human monoclonal antibody against cytomegalovirus. Third communication: correspondence of the idiotype activity and virus neutralization activity of the new monoclonal antibody, regavirumab in rat serum and its pharmacokinetics in rats and monkeys. Arzneimittelforschung. 1994 Jul;44(7):909-13.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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