Trecovirsen

Names

[ CAS No. ]:
153021-75-1

[ Name ]:
Trecovirsen

Biological Activity

[Description]:

Trecovirsen (GEM91) is a 25-mer antisense phosphorothioate oligonucleotide targeted at the gag site of the HIV gene.

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

[References]

[1]. Séréni D, Tubiana R, Lascoux C, et al. Pharmacokinetics and tolerability of intravenous trecovirsen (GEM 91), an antisense phosphorothioate oligonucleotide, in HIV-positive subjects. J Clin Pharmacol. 1999;39(1):47-54.

[2]. Pedziwiatr-Werbicka E, Fuentes E, Dzmitruk V, et al. Novel 'Si-C' carbosilane dendrimers as carriers for anti-HIV nucleic acids: studies on complexation and interaction with blood cells. Colloids Surf B Biointerfaces. 2013;109:183-189.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃₇H₃₁₀N₇₂O₁₃₁P₂₄S₂₄

[ Molecular Weight ]:
7776.331364

Related Compounds

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