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Flurandrenolide

Names

[ CAS No. ]:
1524-88-5

[ Name ]:
Flurandrenolide

[Synonym ]:
flurandrenolide

Biological Activity

[Description]:

Fludroxycortide is a synthetic topical steroid and is used as an anti-inflammatory treatment for use on skin irritations.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.31g/cm3

[ Boiling Point ]:
578.7ºC at 760mmHg

[ Melting Point ]:
209 - 219ºC

[ Molecular Formula ]:
C24H33FO6

[ Molecular Weight ]:
436.51400

[ Flash Point ]:
303.8ºC

[ Exact Mass ]:
436.22600

[ PSA ]:
93.06000

[ LogP ]:
2.49870

[ Vapour Pressure ]:
8.35E-16mmHg at 25°C

[ Index of Refraction ]:
1.572

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TU5024800
CHEMICAL NAME :
Pregn-4-ene-3,20-dione, 6-alpha-fluoro-11-beta,16-alpha,17,21-tetrahydroxy-, cyclic 16,17- acetal with acetone
CAS REGISTRY NUMBER :
1524-88-5
LAST UPDATED :
199710
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C24-H33-F-O6
MOLECULAR WEIGHT :
436.57
WISWESSER LINE NOTATION :
T F5 E5 B666 GO IO RV PUTJ A1 CQ E1 FV1Q H1 H1 OF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TEST SYSTEM :
Human
DOSE/DURATION :
19 mg/kg
REFERENCE :
26UYA8 "Psoriasis, Proceedings of the International Symposium, Stanford, CA, 1971," Farber, E.M., and A.J. Cox, eds., Stanford, CA, Stanford Univ. Press, 1971 Volume(issue)/page/year: -,335,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83059 No. of Facilities: 38 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 713 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83059 No. of Facilities: 56 (estimated) No. of Industries: 3 No. of Occupations: 4 No. of Employees: 11429 (estimated) No. of Female Employees: 10864 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
TU5024800

Synthetic Route

Precursor & DownStream


Related Compounds

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