Kinsenoside

Names

[ Name ]:
Kinsenoside

[Synonym ]:
2(3H)-Furanone, 4-(β-D-glucopyranosyloxy)dihydro-, (4R)-
goodyeroside
(4R)-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-one
(3R)-5-Oxotetrahydro-3-furanyl β-D-glucopyranoside

Biological Activity

[Description]:

Kinsenoside is a main active component isolated from plants of the genus Anoectochilus, and exhibits many biological activities and pharmacological effects[1]. Kinsenoside rescues the nucleus pulposus cells (NPCs) viability under oxidative stress and protects against apoptosis, senescence and mitochondrial dysfunction in a Nrf2-dependent way[2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Inflammation/Immunology

[References]

[1]. Qi CX, et al. Kinsenoside: A Promising Bioactive Compound from Anoectochilus Species. Curr Med Sci. 2018 Feb;38(1):11-18.

[2]. Wang Y, et al. Kinsenoside ameliorates intervertebral disc degeneration through the activation of AKT-ERK1/2-Nrf2 signaling pathway. Aging (Albany NY). 2019 Sep 23;11(18):7961-7977.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
570.2±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₆O₈

[ Molecular Weight ]:
264.229

[ Flash Point ]:
226.2±23.6 °C

[ Exact Mass ]:
264.084503

[ PSA ]:
125.68000

[ LogP ]:
-3.83

[ Vapour Pressure ]:
0.0±3.6 mmHg at 25°C

[ Index of Refraction ]:
1.584

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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