4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone

Names

[ Name ]:
4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone

[Synonym ]:
1-Propanone, 3-(4-hydroxy-2,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)-
3-(4-Hydroxy-2,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone
3-(4-hydroxy-2,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)propan-1-one
Loureirin D

Biological Activity

[Description]:

4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone exhibits COX-1 and COX-2 inhibitory activity[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Immunology/Inflammation >> COX

[Target]

COX-1

COX-2

[References]

[1]. Kittisak Likhitwitayawuid, et al. Flavonoids and stilbenoids with COX-1 and COX-2 inhibitory activity from Dracaena loureiri. Planta Med. 2002 Sep;68(9):841-3.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
532.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₈O₅

[ Molecular Weight ]:
302.322

[ Flash Point ]:
196.7±23.6 °C

[ Exact Mass ]:
302.115417

[ LogP ]:
2.80

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.594

[ Water Solubility ]:
Practically insoluble (0.094 g/L) (25 ºC)

Related Compounds

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