SHMT-IN-1

Names

[ Name ]:
SHMT-IN-1

Biological Activity

[Description]:

SHMT-IN-1 (compound (±)-46) is a potent inhibitor of plasmodial serine hydroxymethyltransferase (SHMT). SHMT-IN-1 has antitumor activity[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

SHMT[1]

[References]

[1]. Witschel MC, et al. Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activities. J Med Chem. 2015 Apr 9;58(7):3117-30.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₆Cl₂N₄O

[ Molecular Weight ]:
375.25

Related Compounds

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