2-chlorophenyl phosphorodichloridate
Names
[ CAS No. ]:
15074-54-1
[ Name ]:
2-chlorophenyl phosphorodichloridate
[Synonym ]:
2-Chlorophenyl phosphorodichloridate
MFCD00009704
2-Chlorophenyl Phosphorodichloridate [Phosphorylating Agent]
EINECS 239-129-4
1-chloro-2-dichlorophosphoryloxybenzene
Chemical & Physical Properties
[ Density]:
1.491 g/mL at 25 °C(lit.)
[ Boiling Point ]:
135-137 °C12 mm Hg(lit.)
[ Molecular Formula ]:
C6H4Cl3O2P
[ Molecular Weight ]:
245.42800
[ Flash Point ]:
221 °F
[ Exact Mass ]:
243.90100
[ PSA ]:
36.11000
[ LogP ]:
4.30450
[ Vapour Pressure ]:
0.0113mmHg at 25°C
[ Index of Refraction ]:
n20/D 1.538(lit.)
[ Storage condition ]:
2-8°C
MSDS
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
C: Corrosive;
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 3265 8/PG 2
[ WGK Germany ]:
3
[ Packaging Group ]:
II
[ Hazard Class ]:
8
[ HS Code ]:
2931900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2931900090
[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%
Articles
J. Chem. Soc. Perkin Trans. I , 2291, (1993)
Dealkylation of nucleoside arylmethyl 2-chlorophenyl phosphates: the 2, 4-dinitrobenzyl protecting group. Christadoulou C and Reese CB.
Tetrahedron Lett. 24(9) , 951-54, (1983)
A new approach to the synthesis of oligonucleotides and their phosphorothioate analogues in solution. Reese CB and Song Q.
Bioorg. Med. Chem. Lett. 7(21) , 2787-92, (1997)