Tiludronate disodium

Names

[ Name ]:
Tiludronate disodium

[Synonym ]:
Disodium [[(4-Chlorophenyl)thio]methylene]bis(hydrogenphosphonate)
Disodium Tiludronate
disodium,[(4-chlorophenyl)sulfanyl-[hydroxy(oxido)phosphoryl]methyl]-hydroxyphosphinate

Biological Activity

[Description]:

Tiludronate disodium (Tiludronic Acid disodium) is a new bisphosphonate, which prevents postmenopausal bone loss. Tiludronate disodium (Tiludronic Acid disodium) presents antiresorptive and anti-inflammatory properties[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

[References]

[1]. Reginster JY, et al. Prevention of postmenopausal bone loss by tiludronate. Lancet. 1989 Dec 23-30;2(8678-8679):1469-71.

[2]. Nunes NLT, et al. Effects of local administration of tiludronic acid on experimental periodontitis in diabetic rats. J Periodontol. 2018 Jan;89(1):105-116.

Chemical & Physical Properties

[ Boiling Point ]:
600.7ºC at 760mmHg

[ Molecular Formula ]:
C₇H₇ClNa₂O₆P₂S

[ Molecular Weight ]:
362.57200

[ Flash Point ]:
317.1ºC

[ Exact Mass ]:
361.89200

[ PSA ]:
165.64000

[ LogP ]:
2.94750

[ Vapour Pressure ]:
2.79E-15mmHg at 25°C

MSDS

Click to get detail MSDS

Related Compounds

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