Uprifosbuvir

Names

[ Name ]:
Uprifosbuvir

[Synonym ]:
Uprifosbuvir
Uridine, 2'-chloro-2'-deoxy-2'-methyl-5'-O-[(R)-[[(1R)-1-methyl-2-(1-methylethoxy)-2-oxoethyl]amino]phenoxyphosphinyl]-
10275
UNII:JW31KPS26S

Biological Activity

[Description]:

Uprifosbuvir is an antiviral agent. Uprifosbuvir is a NS5b inhibitor developed for the research of chronic hepatitis C virus[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HCV

Research Areas >> Infection

[References]

[1]. Klapars A, et al. Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods. Chem Sci. 2021;12(26):9031-9036.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₂₂H₂₉ClN₃O₉P

[ Molecular Weight ]:
545.907

[ Exact Mass ]:
545.132996

[ LogP ]:
1.45

[ Index of Refraction ]:
1.588

[ Storage condition ]:
2-8°C

Related Compounds

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