α‑Amylase-IN-1

Names

[ Name ]:
α‑Amylase-IN-1

Biological Activity

[Description]:

α Amylase-IN-1 (Compound 11) is an α-Amylase inhibitor with an IC50 value of 0.5509 μM. α Amylase-IN-1 has antioxidant activity with an IC50 value of 53.49 μM for scavenging DPPH free radicals. IC50 can be used in the study of diabetes and oxidative stress-related diseases.[1]

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

IC50: 0.5509 μM (α-Amylase), 53.49 μM (DPPH)

[References]

[1]. Ali A, et al. Dihydropyrazole Derivatives Act as Potent α-Amylase Inhibitors and Free Radical Scavengers: Synthesis, Bioactivity Evaluation, Structure-Activity Relationship, ADMET, and Molecular Docking Studies. ACS Omega. 2023 Jun 2;8(23):20412-20422.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₈N₂O₃

[ Molecular Weight ]:
310.35

[ Exact Mass ]:
310.13200

[ PSA ]:
62.13000

[ LogP ]:
2.47190

Related Compounds

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