LHRH (lamprey III) trifluoroacetate salt

Names

[ Name ]:
LHRH (lamprey III) trifluoroacetate salt

[Synonym ]:
Petromyson marinus gonadotropin-releasing hormone III
Glp-His-Trp-Ser-His-Asp-Trp-Lys-Pro-Gly-NH2
luteinizing hormone-releasing hormone isoform III
p-EtO2CC6H4ZnI
gonadotropin-releasing hormone III
pEHWSHDWKPG-NH2

Biological Activity

[Description]:

LGnRH-III, lamprey, an isoform of GnRH isolated from the sea lamprey, is a weak GnRH agonist with antitumor activities[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

GnRH[2]

[References]

[1]. Pappa EV, et al. Structure-activity studies of lGnRH-III through rational amino acid substitution and NMR conformational studies. Biopolymers. 2012;98(6):525-34.

[2]. Manea M, et al. lGnRH-III -- a promising candidate for anticancer drug development. Protein Pept Lett. 2013 Apr;20(4):439-49.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₉H₇₄N₁₈O₁₄

[ Molecular Weight ]:
1259.33

[ Exact Mass ]:
1258.56000

[ PSA ]:
497.79000

[ LogP ]:
1.02120

Related Compounds

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