Niazinin

Names

[ Name ]:
Niazinin

Biological Activity

[Description]:

Niazinin is a thiocarbamate glycoside with antileishmanial activities, with an IC50 value of 5.25 μM. Niazinin also shows a binding affinity with the target protein 3CL protease. Niazinin has promising leishmanicidal, anti-inflammatory and anti-pyretic activity[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> SARS-CoV

Research Areas >> Inflammation/Immunology

[In Vitro]

Niazinin, is cytotoxic at substantially higher concentration (CC50 of 31.6 µM) than its antileishmanial concentration (IC50 of 5.25 µM)[1].

[References]

[1]. Amandeep Kaur, et al. Antileishmanial compounds from Moringa oleifera Lam. Z Naturforsch C J Biosci. Mar-Apr 2014;69(3-4):110-6.

[2]. Shiv Rakesh Naik, et al. Structure-based virtual screening, molecular dynamics and binding affinity calculations of some potential phytocompounds against SARS-CoV-2. J Biomol Struct Dyn. 2021 Mar 8;1-18.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₂₁NO₆S

[ Molecular Weight ]:
343.395

[ Storage condition ]:
2-8℃

Related Compounds

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