AMG2850

Names

[ CAS No. ]:
1470018-52-0

[ Name ]:
AMG2850

Biological Activity

[Description]:

AMG2850 is a potent, orally bioavailable and selective transient receptor potential melastatin 8 (TRPM8) antagonist[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

Research Areas >> Inflammation/Immunology

[Target]

TRPM8[1].

[References]

[1]. Lehto SG, et al. AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia. Naunyn Schmiedebergs Arch Pharmacol. 2015 Apr;388(4):465-76.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₇F₆N₃O

[ Molecular Weight ]:
417.35

Related Compounds

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