NMS-P945

Names

[ CAS No. ]:
1466546-35-9

[ Name ]:
NMS-P945

Biological Activity

[Description]:

NMS-P945 is an ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs). NMS-P945 is suitable for conjugation to mAbs with reproducible Drug Antibody Ratio (DAR) >3.5[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[References]

[1]. Valsasina B, Novel thienoduocarmycin-trastuzumab ADC demonstrates Strong Anti-tumor Efficacy with Favorable Safety Profile in Preclinical Studies. Mol Cancer Ther. 2023 Sep 19.  

Chemical & Physical Properties

[ Molecular Formula ]:
C61H76ClN11O12S

[ Molecular Weight ]:
1222.84

Related Compounds

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