ALK kinase inhibitor-1

Names

[ Name ]:
ALK kinase inhibitor-1

[Synonym ]:
[7-(5-Fluoro-2-methoxyphenyl)-2-{[2-isopropoxy-4-(4-methyl-1-piperazinyl)phenyl]amino}thieno[3,2-d]pyrimidin-6-yl]methanol
Thieno[3,2-d]pyrimidine-6-methanol, 7-(5-fluoro-2-methoxyphenyl)-2-[[2-(1-methylethoxy)-4-(4-methyl-1-piperazinyl)phenyl]amino]-

Biological Activity

[Description]:

ALK kinase inhibitor-1 is an anaplastic lymphoma kinase (ALK) inhibitor extracted from patent US20130261106A1 compound I-202[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK

[References]

[1]. Carry JC, et, al. Novel thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof. US20130261106A1.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
735.9±70.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₈H₃₂FN₅O₃S

[ Molecular Weight ]:
537.649

[ Flash Point ]:
398.8±35.7 °C

[ Exact Mass ]:
537.221008

[ LogP ]:
4.32

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.646

Related Compounds

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