NCGC 607

Names

[ Name ]:
NCGC 607

[Synonym ]:
Benzamide, 2-[2-[(4-iodophenyl)amino]-2-oxoethoxy]-N-[2-(methylphenylamino)-2-oxoethyl]-
2-{2-[(4-Iodophenyl)amino]-2-oxoethoxy}-N-{2-[methyl(phenyl)amino]-2-oxoethyl}benzamide
NCGC607

Biological Activity

[Description]:

NCGC607 is a noninhibitory chaperone of glucocerebrosidase (Gcase)[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

[References]

[1]. Aflaki E, et al. A New Glucocerebrosidase Chaperone Reduces α-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism. J Neurosci. 2016 Jul 13;36(28):7441-52.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
734.5±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₄H₂₂IN₃O₄

[ Molecular Weight ]:
543.354

[ Flash Point ]:
398.0±32.9 °C

[ Exact Mass ]:
543.065491

[ LogP ]:
3.90

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.679

NCGC 607

Names

Biological Activity

Chemical & Physical Properties

Related Compounds