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β-catenin-IN-2

Names

[ CAS No. ]:
1458664-10-2

[ Name ]:
β-catenin-IN-2

Biological Activity

[Description]:

β-catenin-IN-2 is a potent β-catenin inhibitor, compound H1B1, extracted from patent US20150374662A1. β-catenin-IN-2 can be used for the study of colorectal cancer[1].

[Related Catalog]:

Research Areas >> Cancer

[In Vitro]

β-catenin-IN-2 (10-40 μM) suppresses the transcriptional activity of the β-catenin/Tcf-4 in a dose-dependent manner in HCT116 cells[1].

[References]

[1]. Ann Marie Bode, et al. Inhibitors of beta-catenin in treatment of colorectal cancer. Patent US20150374662A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C15H14FN3

[ Molecular Weight ]:
255.29


Related Compounds