N-Phenylrhodanine
Names
[ CAS No. ]:
1457-46-1
[ Name ]:
N-Phenylrhodanine
[Synonym ]:
N-PHENYL-RHODANINE
3-phenyl-2-sulfanylidene-1,3-thiazolidin-4-one
EINECS 215-940-9
Chemical & Physical Properties
[ Density]:
1.45g/cm3
[ Boiling Point ]:
322ºC at 760mmHg
[ Melting Point ]:
190-194ºC
[ Molecular Formula ]:
C9H7NOS2
[ Molecular Weight ]:
209.28800
[ Flash Point ]:
148.5ºC
[ Exact Mass ]:
208.99700
[ PSA ]:
77.70000
[ LogP ]:
2.11630
[ Vapour Pressure ]:
0.000288mmHg at 25°C
[ Index of Refraction ]:
1.736
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VI8465000
- CHEMICAL NAME :
- Rhodanine, 3-phenyl-
- CAS REGISTRY NUMBER :
- 1457-46-1
- BEILSTEIN REFERENCE NO. :
- 0151293
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C9-H7-N-O-S2
- MOLECULAR WEIGHT :
- 209.29
- WISWESSER LINE NOTATION :
- T5SYNV EHJ BUS CR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,558,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1233 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 24,33,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 120 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 126,303,1960
Safety Information
[ Hazard Codes ]:
Xi: Irritant;
[ HS Code ]:
2934999090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%