Mirvetuximab soravtansine

Names

[ CAS No. ]:
1453084-37-1

[ Name ]:
Mirvetuximab soravtansine

Biological Activity

[Description]:

Mirvetuximab soravtansine (IMGN853) is an antibody drug-conjugate (ADC) consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A. Mirvetuximab soravtansine selectively binds to folate receptor 1 (FOLR1). Mirvetuximab soravtansine has an anti-proliferative effect via growth arrest and augmented DNA damage[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Ponte JF, et, al. Mirvetuximab Soravtansine (IMGN853), a Folate Receptor Alpha-Targeting Antibody-Drug Conjugate, Potentiates the Activity of Standard of Care Therapeutics in Ovarian Cancer Models. Neoplasia. 2016 Dec;18(12):775-784.  

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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