CCK2R Ligand-Linker Conjugates 1

Names

[ Name ]:
CCK2R Ligand-Linker Conjugates 1

Biological Activity

[Description]:

CCK2R ligand CRL is a ligand-linker conjugate; which conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) via a hydrophilic peptide linker[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[References]

[1]. Wayua C, et al. Selective Tumor Targeting of Desacetyl Vinblastine Hydrazide and Tubulysin B via Conjugation to a Cholecystokinin 2 Receptor (CCK2R) Ligand. Mol Pharm. 2015 Jul 6;12(7):2477-83.

Chemical & Physical Properties

[ Molecular Formula ]:
C₇₂H₁₁₀N₁₂O₂₇S

[ Molecular Weight ]:
1607.77

Related Compounds

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