20(S)-Hydroxypregn-4-en-3-one
Names
[ CAS No. ]:
145-14-2
[ Name ]:
20(S)-Hydroxypregn-4-en-3-one
[Synonym ]:
20alpha-Dihydroprogesterone
20.α.-Hydroxydihydroprogesterone
BTX
EINECS 205-649-5
20(S)-Hydroxypregn-4-en-3-one
Chemical & Physical Properties
[ Density]:
1.09g/cm3
[ Boiling Point ]:
451.7ºC at 760mmHg
[ Molecular Formula ]:
C21H32O2
[ Molecular Weight ]:
316.47800
[ Flash Point ]:
192.4ºC
[ Exact Mass ]:
316.24000
[ PSA ]:
37.30000
[ LogP ]:
4.51530
[ Vapour Pressure ]:
4.65E-10mmHg at 25°C
[ Index of Refraction ]:
1.549
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU5559900
- CHEMICAL NAME :
- Pregn-4-en-3-one, 20-alpha-hydroxy-
- CAS REGISTRY NUMBER :
- 145-14-2
- BEILSTEIN REFERENCE NO. :
- 2220567
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C21-H32-O2
- MOLECULAR WEIGHT :
- 316.53
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 40 mg/kg
- SEX/DURATION :
- female 10 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 10 mg/L
- REFERENCE :
- AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920- Volume(issue)/page/year: 127,151,1977
Safety Information
[ WGK Germany ]:
3
[ RTECS ]:
TU5559900