2-HYDRAZONO-3-METHYL-2,3-DIHYDROBENZO[D]THIAZOLE HYDROCHLORIDE
Names
[ CAS No. ]:
14448-67-0
[ Name ]:
2-HYDRAZONO-3-METHYL-2,3-DIHYDROBENZO[D]THIAZOLE HYDROCHLORIDE
[Synonym ]:
3-Methyl-2(3H)-benzothiazolonehydrazonehydrochloride
2-Benzothiazolinone,3-methyl-,hydrazone,hydrochloride
3-Methylbenzothiazol-2(3H)-onehydrazoneHCl
3-Methyl-2-benzothiazolinone hydrazone HCI
3-METHYL-2-BENZOTHIAZOLINONE HYDRAZONE HCL
3-METHYLBENZOTHIAZOL-2-ONE HYDRAZONE HYDROCHLORIDE
MBTH HCL
3-Methyl-2-BenzothiazolinoneHydrazoneHcl(Mbth)
2(3H)-Benzothiazolone,3-methyl-,hydrazone,hydrochloride
2-Hydrazono-3-methyl-2,3-dihydrobenzo[d]thiazole hydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
369.6ºC at 760 mmHg
[ Melting Point ]:
276-278℃（分解）
[ Molecular Formula ]:
C8H10ClN3S
[ Molecular Weight ]:
215.70300
[ Flash Point ]:
177.4ºC
[ Exact Mass ]:
215.02800
[ PSA ]:
71.55000
[ LogP ]:
2.51650
[ Vapour Pressure ]:
8.02E-06mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DL7160200
- CHEMICAL NAME :
- 2(3H)-Benzothiazolone, 3-methyl-, hydrazone, hydrochloride
- CAS REGISTRY NUMBER :
- 14448-67-0
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C8-H9-N3-S.Cl-H
- MOLECULAR WEIGHT :
- 215.72
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 149 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes Gastrointestinal - other changes
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >16 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 177 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 12300 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 1 mg/plate
- REFERENCE :
- TIHEEC Toxicology and Industrial Health. (Princeton Scientific Pub. Co., POB 2155, Princeton, NJ 08540) V.1- 1985- Volume(issue)/page/year: 4,23,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6634 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1358 (estimated) No. of Female Employees: 956 (estimated)