CAY10677

Names

[ Name ]:
CAY10677

[Synonym ]:
5-{3-[(Diethylamino)methyl]-1-octyl-1H-indol-5-yl}-2-pyrimidinamine
1H-Indole-3-methanamine, 5-(2-amino-5-pyrimidinyl)-N,N-diethyl-1-octyl-

Biological Activity

[Description]:

CAY10677 (compound 15) is a potent ICMT inhibitor that inhibits cancer cell proliferation. CAY10677 has good PAMPA penetration[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Ramanujulu PM et al. Functionalized indoleamines as potent, drug-like inhibitors of isoprenylcysteine carboxyl methyltransferase (Icmt). Eur J Med Chem. 2013 May;63:378-86.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
600.3±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₅H₃₇N₅

[ Molecular Weight ]:
407.595

[ Flash Point ]:
316.9±34.3 °C

[ Exact Mass ]:
407.304901

[ PSA ]:
60.70000

[ LogP ]:
6.48

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.585

Related Compounds

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