MM-401
Names
Biological Activity
[Description]:
MM-401 is a potent inhibitor for the MLL1-WDR5 interaction with the IC50 of 0.9 nM in disrupting WDR5-MLL1 interaction. MM-401 maintains high binding affinity to WDR5 (Ki<1 nM). MM-401 specifically inhibits MLL1 H3 lysine (K) 4 methyltransferase activity but does not affect other MLL family histone methyltransferases (HMTs). MM-401 can be used for the research of MLL leukemia[1].
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[References]
Chemical & Physical Properties
No Any Chemical & Physical Properties