Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy-

Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy- is an orally available compound suitable for the treatment of heart failure without inducing nausea, vomiting and restlessness.

Signaling Pathways >> Others >> Others

Research Areas >> Cardiovascular Disease

15 mg/kg of compound produces 60% increase in left ventricular contractility in anaesthetized cat. An oral dose of compound (25 mg/kg) could produce marked increases in left ventricular contractility (45%) in conscious dog[1].

[1]. EP0482717A1

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline