M2WJ-332

Names

[ CAS No. ]:
1421958-72-6

[ Name ]:
M2WJ-332

[Synonym ]:
N-{[5-(2-Thienyl)-1,2-oxazol-3-yl]methyl}-1-adamantanamine
3-Isoxazolemethanamine, 5-(2-thienyl)-N-tricyclo[3.3.1.13,7]dec-1-yl-

Biological Activity

[Description]:

A potent inhibitor of drug-resistant S31N mutant of the M2 ion channel of influenza A virus with IC50 of 153 nM; is more potent against S31N than amantadine against the WT M2.

[References]

References 1. Wang J, et al. Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1315-20. View Related Products by Target Influenza Virus

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
465.9±35.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₂₂N₂OS

[ Molecular Weight ]:
314.445

[ Flash Point ]:
235.6±25.9 °C

[ Exact Mass ]:
314.145294

[ LogP ]:
4.42

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.629

Related Compounds

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