CYM 50769

Names

[ Name ]:
CYM 50769

Biological Activity

[Description]:

CYM 50769 is a non-peptidic selective antagonist of neuropeptides B and W receptor 1 (NPBWR1). CYM 50769 can attenuates the NPW-23-induced cell proliferation in ATDC5. CYM 50769 can be used for researching endochondral bone formation[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[Target]

NPBWR1, GPR7[1]

[In Vitro]

CYM 50769 (1 and 3 μM; 30 min) attenuates the NPW-23-induced ATDC5 cell proliferation in a dose-dependent manner[1]. Cell Proliferation Assay Cell Line: ATDC5 (exposed with 200 ng/mL NPW-23 for 24 h)[1] Concentration: 1 and 3 μM Incubation Time: 30 min Result: Attenuated the NPW-23-induced cell proliferation in a dose-dependent manner.

[References]

[1]. Guerrero M, et al. SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists. Bioorg Med Chem Lett. 2013 Feb 1;23(3):614-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₁₇ClN₂O₃

[ Molecular Weight ]:
416.86

[ Exact Mass ]:
416.09300

[ PSA ]:
53.35000

[ LogP ]:
5.31570

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H413

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.